This is the new gorilla from Microchip! The 18F4550 has 16K of flash, 12 MIPs from a 4MHz external crystal (internal PLL up to 96MHz), and a hardware Full Speed USB 2.0 peripheral. That's right, this little guy can communicate directly with USB. Package can be programmed in circuit and even has a dedicated ICD port on the TQFP versions.
Excellent USB tutorial using the 18F4550 by Dan Overholt.
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Documents: 18F4550 Datasheet